Schneider Philipp, Voide Romain, Stampanoni Marco, Müller Ralph
Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.
Biomed Tech (Berl). 2009 Feb;54(1):48-54. doi: 10.1515/BMT.2009.007.
During the last two decades micro-computed tomography has become the method of choice for the non-destructive assessment and quantitative morphometry of hard tissues in three dimensions. With the advent of third-generation synchrotron radiation sources, micro-computed tomography in the micrometer range has become feasible and has been employed to analyze local bone tissue properties. However, owing to limitations regarding the tradeoff between object size and spatial resolution, non-destructive conventional global computed tomography of hard tissues, such as bone, remains unachievable in the submicrometer domain so far. Here, we report on a post-processing technique for the assessment of hard tissues using local synchrotron radiation-based computed tomography, which overcomes this experimental limitation.
在过去二十年中，微计算机断层扫描已成为对硬组织进行三维无损评估和定量形态测量的首选方法。随着第三代同步辐射源的出现，微米级的微计算机断层扫描变得可行，并已用于分析局部骨组织特性。然而，由于在物体尺寸和空间分辨率之间权衡的限制，迄今为止，在亚微米领域仍无法实现对骨等硬组织进行无损常规全局计算机断层扫描。在此，我们报告一种使用基于局部同步辐射的计算机断层扫描评估硬组织的后处理技术，该技术克服了这一实验限制。
