von der Helm K
Proc Natl Acad Sci U S A. 1977 Mar;74(3):911-5. doi: 10.1073/pnas.74.3.911.
The polypeptide precursor pr76 to the internal viral group specific (gs) antigen proteins of Rous sarcoma virus, synthesized in a cell-free system of ascites cells, has been processed in vitro into the viral proteins by purified viral protein p15 as well as by disrupted Rous sarcoma virus. Disrupted Rauscher murine leukemia virus does not stimulate the cleavage process in vitro. Autocatalytic cleavage of the polypeptide precursor pr76 or Rous sarcoma virus, which contains the peptide sequence of p15, is not observed.
劳氏肉瘤病毒内部病毒群特异性(gs)抗原蛋白的多肽前体pr76,在腹水细胞的无细胞系统中合成后,已通过纯化的病毒蛋白p15以及经裂解的劳氏肉瘤病毒在体外加工成病毒蛋白。经裂解的劳斯氏鼠白血病病毒在体外不刺激裂解过程。未观察到含有p15肽序列的多肽前体pr76或劳氏肉瘤病毒的自催化裂解。