Yuasa Toshinori, Miyazaki Chinami, Oh Jae K, Espinosa Raul E, Bruce Charles J
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA.
J Am Soc Echocardiogr. 2009 Mar;22(3):253-60. doi: 10.1016/j.echo.2008.11.027. Epub 2009 Jan 29.
The Tei index is an indicator of systolic and diastolic myocardial performance. We evaluated the Tei index in patients undergoing cardiac resynchronization therapy (CRT).
Forty-two patients were studied before CRT and 1 day and 6 months after CRT, comparing responders with nonresponders.
The Tei index decreased 1 day after CRT (left ventricle [LV]: P < .001, right ventricle [RV]: P = .01) and remained lower at follow-up (LV and RV: P < .001 vs baseline). Responders had a higher LV Tei index at baseline (P = .003) and achieved a sustained improvement in Tei index at follow-up (LV: P < .001, RV: P = .002) in contrast with nonresponders (LV and RV: not significant). Baseline LV Tei index and change in LV Tei index were both correlated with LV end-systolic volume reduction after CRT (r = 0.52, P < .001, r = 0.43, P = .006).
The baseline LV Tei index was significantly higher in responders and exhibited an acute and sustained improvement after CRT. The baseline RV Tei index was similar in responders and nonresponders but improved significantly only in responders.
Tei指数是收缩期和舒张期心肌功能的一个指标。我们评估了接受心脏再同步治疗(CRT)患者的Tei指数。
对42例患者在CRT前、CRT后1天和6个月进行研究,比较反应者和无反应者。
CRT后1天Tei指数降低(左心室[LV]:P <.001,右心室[RV]:P =.01),随访时仍较低(LV和RV:与基线相比P <.001)。反应者在基线时LV Tei指数较高(P =.003),随访时Tei指数持续改善(LV:P <.001,RV:P =.002),而无反应者(LV和RV:无显著性差异)。基线LV Tei指数和LV Tei指数的变化均与CRT后LV收缩末期容积减少相关(r = 0.52,P <.001,r = 0.43,P =.006)。
反应者的基线LV Tei指数显著较高,CRT后呈现急性和持续性改善。反应者和无反应者的基线RV Tei指数相似,但仅反应者有显著改善。