Katagiri K, Fujiwara S, Shinkai H, Takayasu S
Department of Dermatology, Medical College of Oita, Japan.
J Dermatol. 1991 Apr;18(4):211-7. doi: 10.1111/j.1346-8138.1991.tb03070.x.
Thirteen cases among 16,260 patients seen at our department during the nine years from 1981 were diagnosed as pseudoxanthoma elasticum (PXE). The sex and age distributions were similar to those so far reported in the literature. There were two cases of the autosomal dominant type. One patient had skin lesions typical of PXE in association with Ehlers-Danlos syndrome. In two of three patients with cutis laxa-like lesions, eruptions of elastosis perforans serpiginosa were present. In three cases, we failed to detect deposition of calcium in typical skin lesions in either an early or a late stage by histochemical staining, in spite of the presence of slightly degenerated elastic fibers.
在1981年至1990年的9年期间，我科诊治的16260例患者中有13例被诊断为弹性假黄瘤（PXE）。其性别和年龄分布与迄今文献报道的相似。有2例为常染色体显性型。1例患者有典型的PXE皮肤损害并伴有埃勒斯-当洛综合征。在3例有皮肤松弛样损害的患者中，有2例出现匐行性穿通性弹力纤维病疹。在3例患者中，尽管存在轻度退变的弹性纤维，但通过组织化学染色，我们在早期或晚期均未在典型皮肤损害中检测到钙沉积。
