Cunningham Katherine A, Ashrafi Kaveh
Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA.
Cell Metab. 2009 Feb;9(2):113-4. doi: 10.1016/j.cmet.2009.01.008.
The fundamental task of maintaining energy balance is complex when nutrient levels are plentiful, but it becomes even more challenging when nutrients are dynamic or scarce. A recent Nature report delineates a role of the AMP kinase pathway in rationing energy stores for the long-term survival of Caenorhabditis elegans dauers (Narbonne and Roy, 2009).
当营养物质充足时,维持能量平衡的基本任务就很复杂,但当营养物质处于动态变化或稀缺状态时,这一任务就变得更具挑战性。《自然》杂志最近的一篇报道阐述了AMP激酶途径在为秀丽隐杆线虫 dauer 幼虫的长期存活分配能量储备方面的作用(Narbonne和Roy,2009年)。