Garcia-Gallont Rudolf
Department of Surgery, Amedesgua Hospital, Guatemala City, Guatemala.
Dig Dis. 2008;26(4):304-8. doi: 10.1159/000177013. Epub 2009 Jan 30.
Although proton pump inhibitor treatment remains the first-line treatment for gastroesophageal reflux disease (GERD), the panorama of an indefinitely prolonged medical treatment faces patients and physicians with the need to look for an equivalent, more definitive therapy. Facing global results, after many series have demonstrated the safety of the laparoscopic antireflux surgery procedure in experienced hands, with a low incidence of intra- and postoperative morbidity and a short postoperative hospital stay (averaging 2 days), the immediate benefit as well as the long-term alleviation of symptoms (very good: 82%, good: 92%) seem to justify the place of surgical fundoplication in the therapeutic armamentarium for GERD as a valid alternative to medical treatment. Careful patient selection for surgery, a complete and thorough preoperative workup, an intervention in experienced hands, and a patient well informed about the pros and cons of both medical and surgical therapy are mandatory.
尽管质子泵抑制剂治疗仍是胃食管反流病(GERD)的一线治疗方法,但无限期延长药物治疗的现状使患者和医生面临着寻找等效、更明确治疗方法的需求。从总体结果来看,在许多系列研究表明经验丰富的医生进行腹腔镜抗反流手术的安全性后,该手术的术中和术后发病率低,术后住院时间短(平均2天),其即时获益以及症状的长期缓解(非常好:82%,好:92%)似乎证明了手术胃底折叠术在GERD治疗手段中作为药物治疗有效替代方法的地位。仔细选择手术患者、进行全面彻底的术前检查、由经验丰富的医生进行干预以及让患者充分了解药物和手术治疗的利弊是必不可少的。