Trus T L, Laycock W S, Wo J M, Waring J P, Branum G D, Mauren S J, Katz E M, Hunter J G
Department of Digestive Diseases, Emory University, Atlanta, Georgia 30322, USA.
Am J Gastroenterol. 1998 Mar;93(3):351-3. doi: 10.1111/j.1572-0241.1998.00351.x.
Laparoscopic antireflux surgery is indicated in young patients with medication-dependent gastroesophageal reflux disease (GERD), both because of their need for lifelong medical treatment and the need to prevent the complications of GERD. Many elderly patients with GERD have similar concerns. We compared the safety and efficacy of laparoscopic antireflux surgery in the elderly with the results achieved in patients <65 yr.
A total of 359 patients have had laparoscopic antireflux surgery in our hospital, 42 of whom were > or = 65 yr of age. Symptoms were scored from 0 (none) to 4 (severe) before and after surgery. Ambulatory pH monitoring was also performed before and after surgery. Results were compared between age groups with the Mann-Whitney U test.
Elderly patients had significantly higher preoperative American Society of Anesthesiologists (ASA) scores (mean 2.4 vs 2.0) (p = 0.0024), but otherwise there were no significant differences in preoperative symptom scores or pH results. Both groups demonstrated equivalent postoperative improvement in symptoms and 24-h pH study. There was no mortality in either group, and there was no significant difference in morbidity or hospital stay between the two groups.
Laparoscopic antireflux surgery is a safe and effective treatment of GERD in the elderly and should not be refused solely on the basis of age.
对于药物依赖型胃食管反流病(GERD)的年轻患者,需要进行腹腔镜抗反流手术,这既是因为他们需要终身药物治疗,也是为了预防GERD的并发症。许多老年GERD患者也有类似的担忧。我们比较了老年患者腹腔镜抗反流手术的安全性和疗效与65岁以下患者的手术结果。
我院共有359例患者接受了腹腔镜抗反流手术,其中42例年龄≥65岁。术前和术后症状按0(无)至4(严重)评分。术前和术后还进行了动态pH监测。采用Mann-Whitney U检验比较不同年龄组的结果。
老年患者术前美国麻醉医师协会(ASA)评分显著更高(平均2.4比2.0)(p = 0.0024),但术前症状评分或pH结果无显著差异。两组术后症状改善和24小时pH研究结果相当。两组均无死亡病例,两组在发病率或住院时间方面无显著差异。
腹腔镜抗反流手术是治疗老年GERD的一种安全有效的方法,不应仅因年龄而被拒绝。