Puri A, Subin B S, Agarwal M G
Department of Orthopaedic Oncology, Tata Memorial Hospital, E. Borges Road, Parel, Mumbai 400012, India.
J Bone Joint Surg Br. 2009 Feb;91(2):234-9. doi: 10.1302/0301-620X.91B2.21272.
We evaluated the results of fibular centralisation as a stand alone technique to reconstruct defects that occurred after resection of tumours involving the tibial diaphysis and distal metaphysis. Between January 2003 and December 2006, 15 patients underwent excision of tumours of the tibial diaphysis or distal metaphysis and reconstruction by fibular centralisation. Their mean age was 17 years (7 to 40). Two patients were excluded; one died from the complications of chemotherapy and a second needed a below-knee amputation for a recurrent giant-cell tumour. A total of 13 patients were reviewed after a mean follow-up of 29 months (16 to 48). Only 16 of 26 host graft junctions united primarily. Ten junctions in ten patients needed one or more further procedure before union was achieved. At final follow-up 12 of the 13 patients had fully united grafts; 11 walked without aids. The mean time to union at the junctions that united was 12 months (3 to 36). The mean Musculoskeletal Tumor Society Score was 24.7 (16 to 30). Fibular centralisation is a durable reconstruction for defects of the tibial diaphysis and distal metaphysis with an acceptable functional outcome. Stable osteosynthesis is the key to successful union. Additional bone grafting is recommended for patients who need postoperative radiotherapy.
我们评估了腓骨中心化作为一种独立技术用于重建胫骨干和远端干骺端肿瘤切除后出现的骨缺损的效果。2003年1月至2006年12月期间,15例患者接受了胫骨干或远端干骺端肿瘤切除及腓骨中心化重建术。他们的平均年龄为17岁(7至40岁)。两名患者被排除;一名死于化疗并发症,另一名因复发性巨细胞瘤需要进行膝下截肢。平均随访29个月(16至48个月)后,对总共13例患者进行了复查。26个宿主移植物连接点中只有16个实现了一期愈合。10例患者的10个连接点在实现愈合之前需要进行一次或多次进一步手术。在最后随访时,13例患者中有12例的移植物完全愈合;11例患者无需辅助行走。实现愈合的连接点的平均愈合时间为12个月(3至36个月)。肌肉骨骼肿瘤学会平均评分为24.7(16至30)。腓骨中心化是一种用于胫骨干和远端干骺端骨缺损的持久重建方法,功能结果可接受。稳定的骨固定是成功愈合的关键。对于需要术后放疗的患者,建议进行额外的植骨。