Steiger Hans-Jakob, Göppert Mathias, Floeth Frank, Turowski Bernd, Sabel Michael
Department of Neurosurgery, Heinrich-Heine-University Medical School, Düsseldorf, Germany.
Acta Neurochir (Wien). 2009 Feb;151(2):137-40. doi: 10.1007/s00701-008-0160-x. Epub 2009 Feb 5.
A total 17 fronto-mesial grade II and III gliomas among a total of 64 frontal grade II and III gliomas underwent surgical resection between January 2003 and June 2007. Eleven fronto-mesial gliomas originated from the anterior cingulate gyrus, while the others originated from the genu of the corpus callosum. None of the grade II or III gliomas originated from the gyrus rectus. Anterior cingulate gliomas exhibited distinct features with regard to presenting symptoms, MRI, histopathology and prognosis. Epilepsy was the dominant presenting symptom of anterior cingulate tumours. Five of the 11 gliomas had a sharp border on MRI. Four of the 11 were histopathologically classified as WHO grade II and seven as WHO grade III and an oligodendrocytic component was apparent in eight of the 11 specimens. Comparison of the post-operative survival with the entire set of frontal gliomas showed a trend that anterior cingulate tumours had a more favourable prognosis.
2003年1月至2007年6月期间，在64例额叶II级和III级胶质瘤中，共有17例额内侧II级和III级胶质瘤接受了手术切除。11例额内侧胶质瘤起源于前扣带回，其余起源于胼胝体膝部。II级或III级胶质瘤均未起源于直回。前扣带回胶质瘤在症状表现、MRI、组织病理学和预后方面具有明显特征。癫痫是前扣带回肿瘤的主要症状表现。11例胶质瘤中有5例在MRI上边界清晰。11例中有4例在组织病理学上被分类为WHO II级，7例为WHO III级，11例标本中有8例可见少突胶质细胞成分。与整个额叶胶质瘤组的术后生存率比较显示，前扣带回肿瘤有预后更良好的趋势。
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