Engel H J, Collignon P J, Whiting P T, Kennedy K J
Australian National University, Canberra, Australia.
Eur J Clin Microbiol Infect Dis. 2009 Jul;28(7):821-4. doi: 10.1007/s10096-009-0707-7. Epub 2009 Feb 5.
The purpose of this paper was to determine the population incidence and clinical features of Serratia sp. bacteremia in Canberra, Australia. Demographic and clinical data were collected prospectively for episodes of Serratia sp. bacteremia over a 10-year period, and was confined to Canberra residents using residential postal codes. Thirty-eight episodes of Serratia sp. bacteremia occurred, with a yearly incidence of 1.03 per 100,000 population. The majority of episodes occurred in males (68%). The respiratory tract was the most common focus of infection (21%). Twenty-nine percent of episodes were community-associated. A further 18% of episodes had their onset in the community but were healthcare-associated. The 7-day and 6-month mortality rates were 5 and 37%, respectively. Antibiotic resistance to gentamicin (3%) and ciprofloxacin (0%) was low. Serratia sp. bacteremia is more common than generally appreciated, with a large proportion (47%) of episodes having their onset in the community.
本文旨在确定澳大利亚堪培拉地区沙雷氏菌属菌血症的人群发病率及临床特征。前瞻性收集了10年间沙雷氏菌属菌血症发作的人口统计学和临床数据,且仅限于使用住宅邮政编码的堪培拉居民。共发生38例沙雷氏菌属菌血症,年发病率为每10万人1.03例。大多数发作发生在男性中(68%)。呼吸道是最常见的感染部位(21%)。29%的发作与社区相关。另有18%的发作在社区起病,但与医疗保健相关。7天和6个月死亡率分别为5%和37%。对庆大霉素(3%)和环丙沙星(0%)的抗生素耐药性较低。沙雷氏菌属菌血症比一般认为的更为常见,很大一部分发作(47%)在社区起病。