Reuschel S A, Smith F P
Department of Criminal Justice, University of Alabama, Birmingham.
J Forensic Sci. 1991 Jul;36(4):1179-85.
Benzoylecgonine (BE) was detected in hair samples using nonproprietary extraction methodology and modifications of well-established radioimmunoassay (RIA) screening/quantitative gas chromatography/mass spectrometry (GC/MS) confirmation procedures. Samples collected anonymously from a population of 48 jail detainees weighed between 5.3 and 61.2 mg. All of the 22 hair samples which had RIA results indicating the presence of BE or immunologically similar substances above a cutoff amount of 1.25 ng/sample (50 ng/mL) were confirmed by GC/MS. Several varieties of hair color and texture were tested, although in each general category there were samples which contained BE as well as other samples which did not reveal detectable amounts of BE. The range of concentrations in 22 hair extracts that screened positive were 0.26 to 18 ng/mg hair as determined by GC/MS. In comparison with other reports of cocaine-related substances in hair, these data show consistent concentrations.
使用非专利提取方法以及对成熟的放射免疫分析（RIA）筛查/定量气相色谱/质谱（GC/MS）确证程序进行修改后，在毛发样本中检测到了苯甲酰爱康宁（BE）。从48名监狱被拘留者群体中匿名收集的样本重量在5.3至61.2毫克之间。所有22份RIA结果表明存在BE或免疫类似物质且高于1.25纳克/样本（50纳克/毫升）临界值的毛发样本均通过GC/MS得到确证。测试了几种不同颜色和质地的毛发，尽管在每个大类中都有含有BE的样本以及未检测到可检测量BE的其他样本。经GC/MS测定，22份筛查呈阳性的毛发提取物中的浓度范围为0.26至18纳克/毫克毛发。与其他关于毛发中可卡因相关物质的报告相比，这些数据显示出一致的浓度。
