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Pharmacological studies on meprobamate incorporation in human beard hair.

作者信息

Kintz P, Tracqui A, Mangin P

机构信息

Institut de Médecine Légale, Strasbourg, France.

出版信息

Int J Legal Med. 1993;105(5):283-7. doi: 10.1007/BF01370386.

DOI:10.1007/BF01370386
PMID:8471546
Abstract

The time course of appearance of meprobamate in beard hair after single oral administration (400, 800, or 1200 mg) was monitored in 3 groups of 4 subjects by GC/MS. Meprobamate appeared in beard hair approximately 4-5 days after administration and peaked during the 7-9th day. Drug levels in beard hair appeared to be dose-related.

摘要

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本文引用的文献

1
Toxicological detection of pholcodine and its metabolites in urine and hair using radio immunoassay, fluorescence polarisation immunoassay, enzyme immunoassay, and gas chromatography-mass spectrometry.使用放射免疫测定法、荧光偏振免疫测定法、酶免疫测定法和气相色谱-质谱联用技术对尿液和毛发中的福尔可定及其代谢物进行毒理学检测。
Int J Legal Med. 1990 Dec;104(1):43-6. doi: 10.1007/BF01816483.
2
Determination of meprobamate in human plasma, urine, and hair by gas chromatography and electron impact mass spectrometry.气相色谱法和电子轰击质谱法测定人血浆、尿液及毛发中的眠尔通
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Opiate levels in hair.毛发中的阿片类物质水平。
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Results of comparative determination of morphine in human hair using RIA and GC/MS.
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Drug screening in an unconventional matrix: hair analysis.非常规基质中的药物筛查：毛发分析
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[Tetrahydrocannabinols in hair of hashish smokers].
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Testing human hair for drugs of abuse. I. Individual dose and time profiles of morphine and codeine in plasma, saliva, urine, and beard compared to drug-induced effects on pupils and behavior.检测人体毛发中的滥用药物。I. 与药物对瞳孔和行为的影响相比，血浆、唾液、尿液和胡须中吗啡和可待因的个体剂量和时间分布情况。
J Anal Toxicol. 1990 Jan-Feb;14(1):1-7. doi: 10.1093/jat/14.1.1.
9
The measurement of haloperidol and reduced haloperidol in hair as an index of dosage history.将毛发中氟哌啶醇及还原氟哌啶醇的测量作为用药史指标。
Br J Clin Pharmacol. 1990 Feb;29(2):187-94. doi: 10.1111/j.1365-2125.1990.tb03618.x.
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The determination of drugs and their substitutes in human hairs.人发中药物及其替代物的测定。
Forensic Sci Int. 1990 May-Jun;46(1-2):17-8. doi: 10.1016/0379-0738(90)90124-h.