Gardner M B, Rasheed S, Klement V, Rongey R W, Brown J C, Dworsky R, Henderson B E
UCLA Forum Med Sci. 1976(19):217-34.
In certain genetically susceptible populations of wild mice a progressive motor neuron disease with a long latent period is caused by indigenous type C leukemia virus. Neuronal damage appears to be due primarily to a direct neurotropic effect of the virus and not to an immunogenic mechanism. The disease can be prevented by antiviral genetic means. Search for a similar virus in humans with ALS has been negative.
在某些基因易感性的野生小鼠群体中，一种潜伏期长的进行性运动神经元疾病是由本土C型白血病病毒引起的。神经元损伤似乎主要是由于病毒的直接嗜神经作用，而非免疫机制。这种疾病可以通过抗病毒基因手段预防。在患有肌萎缩侧索硬化症（ALS）的人类中寻找类似病毒的研究结果为阴性。
