Nagamitsu Tohru, Marumoto Kaori, Nagayasu Asami, Fukuda Takeo, Arima Shiho, Uchida Ryuji, Ohshiro Taichi, Harigaya Yoshihiro, Tomoda Hiroshi, Omura Satoshi
School of Pharmacy, Kitasato University, Minato-ku, Tokyo, Japan.
J Antibiot (Tokyo). 2009 Feb;62(2):69-74. doi: 10.1038/ja.2008.12. Epub 2009 Jan 23.
The total synthesis of (-)-amidepsine B, a potent diacylglycerol acyltransferase inhibitor, has been achieved. This synthetic study resulted in the revision of the previously assigned stereostructure of the natural amidepsine B and determined the absolute configuration.
强效二酰基甘油酰基转移酶抑制剂（-）-酰胺普辛B的全合成已完成。这项合成研究导致对天然酰胺普辛B先前指定的立体结构进行了修正，并确定了其绝对构型。
