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用于后颅窝手术的胶原基质硬脑膜成形术:52例成年患者手术技术评估。临床文章。

Collagen matrix duraplasty for posterior fossa surgery: evaluation of surgical technique in 52 adult patients. Clinical article.

作者信息

Narotam Pradeep K, Qiao Fan, Nathoo Narendra

机构信息

Union Hospital Neuroscience, Terre Haute, Indiana, USA.

出版信息

J Neurosurg. 2009 Aug;111(2):380-6. doi: 10.3171/2008.10.JNS08993.

Abstract

OBJECT

Complete dural closure is not always possible following posterior fossa surgery, often requiring a graft to secure complete closure. The authors report their experience of using a collagen matrix as an onlay dural graft for repair of a posterior fossa dural defect.

METHODS

A retrospective analysis was performed in 52 adult patients who had undergone collagen matrix duraplasty for the posterior fossa. Complications directly related to the dural graft, the presence or absence of hydrocephalus, and the role of closed suction wound drainage in relation to postsurgical pseudomeningoceles were analyzed.

RESULTS

The indication for posterior fossa surgery was tumors in 32 patients, vascular abnormalities in 9 patients, and spontaneous cerebellar hemorrhage in 11 patients. Closed suction wound drainage was used in 23 patients (44.2%). Forty-eight (92.3%) of 52 patients had a dural defect > 2 cm. Nine (81.8%) of 11 patients with hydrocephalus required ventriculoperitoneal shunts. Complications of the surgery included pseudomeningoceles in 2 patients (3.8%; no closed suction wound drainage); superficial wound infections in 1 patient (1.9%; with closed suction wound drainage); and unexplained eosinophilia in 1 patient.

CONCLUSIONS

Duraplasty using a collagen matrix is safe and effective in the posterior fossa, and is easy to use and time efficient. Meticulous layered wound closure, the detection and effective control of hydrocephalus, and the use of closed suction wound drainage reduces complications related to collagen matrix duraplasty for the posterior fossa.

摘要

目的

后颅窝手术后并非总能实现硬脑膜的完全闭合,常常需要移植材料来确保完全闭合。作者报告了他们使用胶原基质作为覆盖硬脑膜移植材料修复后颅窝硬脑膜缺损的经验。

方法

对52例接受后颅窝胶原基质硬脑膜成形术的成年患者进行回顾性分析。分析了与硬脑膜移植直接相关的并发症、脑积水的有无以及闭式负压伤口引流在术后假性脑膜膨出方面的作用。

结果

后颅窝手术的指征为32例患者患有肿瘤,9例患者存在血管异常,11例患者为自发性小脑出血。23例患者(44.2%)使用了闭式负压伤口引流。52例患者中有48例(92.3%)硬脑膜缺损大于2 cm。11例脑积水患者中有9例(81.8%)需要进行脑室腹腔分流术。手术并发症包括2例患者出现假性脑膜膨出(3.8%;未使用闭式负压伤口引流);1例患者出现浅表伤口感染(1.9%;使用了闭式负压伤口引流);1例患者出现不明原因的嗜酸性粒细胞增多。

结论

在颅后窝使用胶原基质进行硬脑膜成形术是安全有效的,且易于使用、节省时间。细致的分层伤口缝合、脑积水的检测与有效控制以及闭式负压伤口引流的使用可减少与颅后窝胶原基质硬脑膜成形术相关的并发症。

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