Selective Utrecht Medical Master, University Medical Center Utrecht, Utrecht University, The Netherlands.
J Perinat Med. 2009;37(3):293-6. doi: 10.1515/JPM.2009.040.
To describe the clinical course of infants recovering spontaneously from diaphragmatic paralysis due to perinatal phrenic nerve injury as well as those that underwent plication of the diaphragm.
Between 1990 and 2006, 14 newborns admitted to the Neonatal Intensive Care Unit (NICU) of the Wilhelmina Children's Hospital in Utrecht, The Netherlands, were diagnosed with diaphragmatic paralysis due to obstetric phrenic nerve injury. The clinical and follow-up data were studied retrospectively.
Four infants recovered spontaneously and could be weaned from mechanical ventilation within nine days without further treatment. Plication of the diaphragm was performed in 10 infants because of failure to wean from ventilatory support or serious persistent respiratory distress. Time between birth and plication ranged from 10 to 51 days, with a median of 19 days. Satisfactory respiratory outcome was achieved in 86% of the cases.
The minority of infants suffering from diaphragmatic paralysis due to perinatal phrenic nerve injury recovers spontaneously. Infants who fail to wean from ventilatory support and undergo early plication have a quick recovery and can be extubated successfully within a few days.
描述新生儿因围产期膈神经损伤而自发恢复的膈神经麻痹的临床过程,以及那些接受膈神经折叠术的患者的临床过程。
1990 年至 2006 年期间,荷兰乌得勒支市威廉敏娜儿童医院新生儿重症监护病房(NICU)收治了 14 例因产科膈神经损伤而导致膈神经麻痹的新生儿。回顾性研究了这些患儿的临床和随访数据。
4 例患儿自发性恢复,无需进一步治疗,9 天内即可脱机。10 例患儿因无法脱机或严重持续呼吸窘迫而行膈神经折叠术。出生至折叠术的时间间隔为 10 至 51 天,中位数为 19 天。86%的病例取得了满意的呼吸结局。
少数因围产期膈神经损伤而导致膈神经麻痹的婴儿可自发恢复。无法脱机而行早期折叠术的患儿恢复迅速,可在数天内成功拔管。