肝移植术后原发性中枢神经系统淋巴瘤采用立体定向放射外科联合分次放射治疗。
Primary central nervous system lymphoma after liver transplantation treated by radiosurgery combined with fractionated radiotherapy.
作者信息
Kim Min-Su, Lee Jung-Il, Kim Won-Seok, Ko Yung-Hye
机构信息
Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul, 135-710, South Korea.
出版信息
J Clin Neurosci. 2009 Apr;16(4):583-5. doi: 10.1016/j.jocn.2008.05.016. Epub 2009 Feb 5.
Post-transplant primary central nervous system lymphoma is a rare malignant tumor. A 65-year-old man underwent orthotopic liver transplantation for liver carcinoma. Nine months later, he presented with left-sided motor weakness and MRI of the brain showed a rim-enhancing mass in the right paracentral area. The diagnosis of Epstein-Barr virus-positive diffuse large B-cell lymphoma was confirmed through stereotactic biopsy. The authors report a case of post-transplant primary central nervous system lymphoma after liver transplantation that was treated successfully by gamma knife radiosurgery combined with fractionated whole brain radiotherapy.
移植后原发性中枢神经系统淋巴瘤是一种罕见的恶性肿瘤。一名65岁男性因肝癌接受原位肝移植。9个月后，他出现左侧肢体运动无力，脑部MRI显示右中央旁区域有一个环形强化肿块。通过立体定向活检确诊为爱泼斯坦-巴尔病毒阳性弥漫性大B细胞淋巴瘤。作者报告了一例肝移植后移植后原发性中枢神经系统淋巴瘤病例，该病例通过伽玛刀放射外科联合分次全脑放疗成功治疗。
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