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专科重症监护病房与综合重症监护病房的危重病治疗结果。

Critical illness outcomes in specialty versus general intensive care units.

作者信息

Lott Jason P, Iwashyna Theodore J, Christie Jason D, Asch David A, Kramer Andrew A, Kahn Jeremy M

机构信息

University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

出版信息

Am J Respir Crit Care Med. 2009 Apr 15;179(8):676-83. doi: 10.1164/rccm.200808-1281OC. Epub 2009 Feb 6.

Abstract

RATIONALE

General intensive care units (ICUs) provide care across a wide range of diagnoses, whereas specialty ICUs provide diagnosis-specific care. Risk-adjusted outcome differences across such units are unknown.

OBJECTIVES

To determine the association between specialty ICU care and the outcome of critical illness.

METHODS

We conducted a retrospective cohort study design analyzing patients admitted to 124 ICUs participating in the Acute Physiology and Chronic Health Evaluation IV from January 2002 to December 2005. We examined 84,182 patients admitted to specialty and general ICUs with an admitting diagnosis or procedure of acute coronary syndrome, ischemic stroke, intracranial hemorrhage, pneumonia, abdominal surgery, or coronary-artery bypass graft surgery. ICU type was determined by a local data coordinator at each site. Patients were classified by admission to a general ICU, a diagnosis-appropriate ("ideal") specialty ICU, or a diagnosis-inappropriate ("non-ideal") specialty ICU. The primary outcomes were in-hospital mortality and ICU length of stay.

MEASUREMENTS AND MAIN RESULTS

After adjusting for important confounders, there were no significant differences in risk-adjusted mortality between general versus ideal specialty ICUs for all conditions other than pneumonia. Risk-adjusted mortality was significantly greater for patients admitted to non-ideal specialty ICUs. There was no consistent effect of specialization on length of stay for all patients or for ICU survivors.

CONCLUSIONS

Ideal specialty ICU care appears to offer no survival benefit over general ICU care for select common diagnoses. Non-ideal specialty ICU care (i.e., "boarding") is associated with increased risk-adjusted mortality.

摘要

原理

综合重症监护病房(ICU)针对广泛的诊断提供护理,而专科ICU提供针对特定诊断的护理。此类病房之间经风险调整后的结局差异尚不清楚。

目的

确定专科ICU护理与危重病结局之间的关联。

方法

我们进行了一项回顾性队列研究设计,分析了2002年1月至2005年12月期间参与急性生理与慢性健康状况评估IV的124个ICU收治的患者。我们检查了84182例因急性冠状动脉综合征、缺血性中风、颅内出血、肺炎、腹部手术或冠状动脉搭桥手术等入院诊断或手术而入住专科和综合ICU的患者。每个地点的当地数据协调员确定ICU类型。患者按入住综合ICU、诊断匹配(“理想”)的专科ICU或诊断不匹配(“非理想”)的专科ICU进行分类。主要结局为住院死亡率和ICU住院时间。

测量指标与主要结果

在对重要混杂因素进行调整后,除肺炎外,所有疾病的综合ICU与理想专科ICU之间经风险调整后的死亡率无显著差异。入住非理想专科ICU的患者经风险调整后的死亡率显著更高。专业化对所有患者或ICU幸存者的住院时间没有一致的影响。

结论

对于某些常见诊断,理想的专科ICU护理似乎并不比综合ICU护理更具生存优势。非理想的专科ICU护理(即“收容”)与经风险调整后的死亡率增加相关。

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