Casto Bruce C, Sharma Smita, Fisher James L, Knobloch Thomas J, Agrawal Amit, Weghorst Christopher M
College of Public Health, The Ohio State University, Department of Otolaryngology-Head and Neck Surgery, and James Cancer Hospital/Solove Research Institute, Columbus, OH 43210, USA.
J Health Care Poor Underserved. 2009 Feb;20(1):274-85. doi: 10.1353/hpu.0.0097.
Oral cancer accounts for 2.3% of malignancies in the U.S. and has one of the lowest five-year survival rates. An examination of oral cancer in Appalachia was motivated by the high incidence of lung and bronchial cancers in Appalachian states, the risk factors for which overlap with those for oral cancer. The incidence and mortality rates for oral cancer in 13 Appalachian states and the relative frequency of presumptive risk factors were examined and compared with national rates, using data from the National Program of Cancer Registries, Surveillance Epidemiology and End Results, Behavioral Risk Factor Surveillance System, the Appalachian Regional Commission, and the National Health Interview Survey. Combined incidence rates for oral cancer were higher in six of 12 Appalachian states, and mortality rates higher in 10 of 13, compared with the national average. Smoking was more prevalent than the national average in nine of 13 states, whereas alcohol consumption was the same or less in 11 Appalachian states. Only five of 13 states averaged fewer than the recommended five or more servings per day of fruits and vegetables.
口腔癌占美国恶性肿瘤的2.3%，其五年生存率是最低的之一。对阿巴拉契亚地区口腔癌的调查是受阿巴拉契亚各州肺癌和支气管癌的高发病率推动的，因为这些癌症的风险因素与口腔癌的风险因素重叠。利用来自国家癌症登记计划、监测流行病学和最终结果、行为风险因素监测系统、阿巴拉契亚区域委员会以及国家健康访谈调查的数据，对13个阿巴拉契亚州的口腔癌发病率和死亡率以及假定风险因素的相对频率进行了检查，并与全国发病率进行了比较。与全国平均水平相比，12个阿巴拉契亚州中有6个州的口腔癌综合发病率更高，13个州中有10个州的死亡率更高。13个州中有9个州的吸烟率高于全国平均水平，而11个阿巴拉契亚州的酒精消费量与全国平均水平持平或更低。13个州中只有5个州平均每天摄入的水果和蔬菜少于建议的五份或更多份。
