Majunke N, Wallenborn J, Wunderlich N, Sievert H
CardioVascular Center Frankfurt, Frankfurt, Germany.
Minerva Cardioangiol. 2009 Feb;57(1):103-15.
Intracardiac defects such as atrial septal defect (ASD) and patent foramen ovale (PFO) are common forms of congenital intracardiac apertures which can be successfully closed percutaneously. Since the initial description of an atrial septal defect closure device in the mid 1970s by King and Mills, transcatheter closure of atrial septal defects and patent foramen ovale using various devices has now become an established practice in many centers. The left atrial appendage is a trabeculated remnant of the embryonic left atrium. This is an important source of emboli related to atrial fibrillation. Closure of the left atrial appendage is designed to reduce the risk of stroke in patients with atrial fibrillation. This article reviews the current indications and latest developments in catheter closure of PFO, ASD and left atrial appendage.
心内缺损，如房间隔缺损（ASD）和卵圆孔未闭（PFO），是常见的先天性心内孔洞形式，可通过经皮方式成功闭合。自20世纪70年代中期King和Mills首次描述房间隔缺损封堵装置以来，使用各种装置经导管闭合房间隔缺损和卵圆孔未闭现已在许多中心成为一种既定的做法。左心耳是胚胎左心房的小梁化残余部分。这是与心房颤动相关的栓子的重要来源。闭合左心耳旨在降低心房颤动患者中风的风险。本文综述了PFO、ASD和左心耳导管闭合的当前适应证及最新进展。
