[病例对照研究中的肥胖]
[Obesity in CASE-J Study].
作者信息
Hirata Masakazu, Oba Kouji, Ueshima Kenji, Nakao Kazuwa
机构信息
Department of Medicine and Medical Science, Kyoto University Graduate School of Medicine.
出版信息
Nihon Rinsho. 2009 Feb;67(2):404-7.
PMID:19202919
Abstract
Obesity is closely associated with development of hypertension. Adipose tissue produces molecules of renin-angiotensin system, which contribute to metabolic as well as cardiovascular disorders that develop in obesity. CASE-J Study demonstrated the usefulness of angiotensin receptor blockade in preventing new onset diabetes in obese hypertensive patients.
摘要
肥胖与高血压的发生密切相关。脂肪组织会产生肾素-血管紧张素系统的分子，这些分子会导致肥胖时出现的代谢以及心血管紊乱。CASE-J研究证明了血管紧张素受体阻滞剂在预防肥胖高血压患者新发糖尿病方面的有效性。
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