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[嗅鞘细胞修复脊髓损伤的研究进展]

[An update of repairing spinal cord injury by olfactory ensheathing cells].

作者信息

Hu Zhi-jun, Ma Ying-hui

机构信息

Department of Orthopaedics, Longhua Hospital of Shanghai University of TCM, Shanghai 200032, China.

出版信息

Zhongguo Gu Shang. 2009 Jan;22(1):68-71.

Abstract

The treatment of spinal cord injury is always a stubborn problem for neurosurgeons because nerve cell cannot regenerate and the glia scar can prevent the axonal regeneration. Olfactory ensheathing cells (OECs) is a kind of especial glia cell, which possesses the character of horizontal cell of central nervous system and schwann cell. Many foundational and clinical studies showed that the olfactory ensheathing cellscan promote axonal regeneration and prove axonal growth, some progress is made and this is bringing hope for treatment of spine injury.

摘要

脊髓损伤的治疗一直是神经外科医生面临的棘手问题,因为神经细胞无法再生,且胶质瘢痕会阻碍轴突再生。嗅鞘细胞是一种特殊的胶质细胞,兼具中枢神经系统水平细胞和施万细胞的特性。许多基础和临床研究表明,嗅鞘细胞能够促进轴突再生并支持轴突生长,已取得了一些进展,这为脊髓损伤的治疗带来了希望。

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