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社会人口学因素与孕期宫颈长度

Socio-demographic factors and cervical length in pregnancy.

作者信息

Petrović Dorde, Novakov-Mikić Aleksandra, Mandić Vesna

机构信息

Klinicki centar Vojvodine, Novi Sad, Klinika za ginekologiju i akuserstvo.

出版信息

Med Pregl. 2008 Sep-Oct;61(9-10):443-51. doi: 10.2298/mpns0810443p.

Abstract

The cervical length is an important factor in the risk evaluation of preterm delivery. The aim of this work was to determine the correlation between the cervical length and the demographic characteristics. A transversal type prospective study was done on a sample of 579 pregnant women at various gestational age of low risk mono-fetal pregnancy. The cervical length was measured by trans-vaginal ultrasound procedure within the regular pregnancy monitoring process. The following data were taken into consideration: the woman's age, her body mass at the beginning of the pregnancy and her height in order to calculate the body mass index as well as her smoking habit at the moment of conception. The mean cervical length was 34.3 mm and 35 mm in the group of women aged 30 and less and 31 and over, respectively. The cervix was insignificantly shorter in younger women (being 34.9 mm/35.9 mm in the 1st trimester, 34.5 mm/35.1 mm in the 2nd one and 33.9 mm/34.7 mm in the 3rd trimester). The sample of 579 pregnant women consisted of 448 non-smokers and 131 smokers. The difference in the length of the cervix in smokers and nonsmokers was not significant (being 32.2 mm/35.9 mm; 35 mm/34 mm and 34.4 mm/33.5 mm in the 1st, 2nd and 3rd trimester, respectively). The correlation between the body mass index and the cervical length was analyzed by trimesters. In the first trimester the increase in the body mass index was followed by the shortening of the cervix; the cervical length was not affected by the BAI in the second trimester, whereas the higher the body mass index the longer the cervix in the third trimester. Our study has shown that the cervical length is affected neither by the age of the woman nor her smoking habit but it is affected by the body mass index at the moment of conception, that linear trend being negative in the 1st trimester but positive in the 3rd one. Since the cervical length may be affected not only by the socio-demographic characteristics but the gynecologic obstetric history of the woman as well, we strongly suggest further investigations in this field.

摘要

宫颈长度是早产风险评估中的一个重要因素。这项研究的目的是确定宫颈长度与人口统计学特征之间的相关性。对579例不同孕周的低风险单胎妊娠孕妇进行了横向前瞻性研究。在常规孕期监测过程中,通过经阴道超声测量宫颈长度。考虑了以下数据:孕妇年龄、妊娠开始时的体重和身高,以计算体重指数,以及受孕时的吸烟习惯。30岁及以下和31岁及以上女性组的平均宫颈长度分别为34.3毫米和35毫米。年轻女性的宫颈稍短(孕早期为34.9毫米/35.9毫米,孕中期为34.5毫米/35.1毫米,孕晚期为33.9毫米/34.7毫米)。579例孕妇样本中,有448例不吸烟者和131例吸烟者。吸烟者和非吸烟者的宫颈长度差异不显著(孕早期分别为32.2毫米/35.9毫米,孕中期为35毫米/34毫米,孕晚期为34.4毫米/33.5毫米)。按孕期分析体重指数与宫颈长度之间的相关性。在孕早期,体重指数增加后宫颈缩短;孕中期宫颈长度不受体重指数影响,而孕晚期体重指数越高宫颈越长。我们的研究表明,宫颈长度既不受孕妇年龄影响,也不受吸烟习惯影响,但受受孕时体重指数影响,这种线性趋势在孕早期为负,在孕晚期为正。由于宫颈长度不仅可能受社会人口统计学特征影响,还可能受孕妇的妇产科病史影响,我们强烈建议在该领域进一步开展研究。

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