中度高血压男性静息及最大运动时左心室质量与收缩压之间的相关性。
Correlations between left ventricular mass and systolic blood pressure at rest and during maximal exercise in moderately hypertensive men.
作者信息
Knutsen K M, Michelsen S, Otterstad J E, Frøland G, Wasenius A, Stugaard M
机构信息
Medical Department, Vestfold Central Hospital, Tønsberg, Norway.
出版信息
J Hum Hypertens. 1991 Jun;5(3):149-54.
We examined 87 men with moderate hypertension (diastolic blood pressure, DPB, greater than or equal to 95 and less than 110 mmHg) (mean age 45, range 22-64, years) with echocardiography and maximal ergometer bicycle test. Left ventricular mass index (LVMI) was calculated according to the Penn convention. Mean LVMI was 126 (60-210) g/m2. The maximal systolic blood pressure (SBP) during exercise was on average 217 (155-260) mmHg. Linear regression analysis revealed a significant correlation between LVMI and SBP at rest (r = 0.48, P less than 0.001) and during exercise (r = 0.39, P less than 0.001). Multiple regression analysis correcting for differences in age, cumulative work and cholesterol level revealed a significant correlation between LVMI and SBP at rest (t = 4.07, P less than 0.0001) and during exercise (t = 3.25, P = 0.002). Thus in patients with established, moderate hypertension exercise SBP is not more predictable for LVMI than is SBP at rest.
我们对87名中度高血压男性患者（舒张压大于或等于95且小于110 mmHg）（平均年龄45岁，范围22 - 64岁）进行了超声心动图检查和最大运动强度的测力计自行车测试。左心室质量指数（LVMI）根据宾夕法尼亚州标准计算。平均LVMI为126（60 - 210）g/m²。运动期间的最大收缩压（SBP）平均为217（155 - 260）mmHg。线性回归分析显示，静息时LVMI与SBP之间存在显著相关性（r = 0.48，P < 0.001），运动期间也存在显著相关性（r = 0.39，P < 0.001）。校正年龄、累积工作量和胆固醇水平差异后的多元回归分析显示，静息时LVMI与SBP之间存在显著相关性（t = 4.07，P < 0.0001），运动期间也存在显著相关性（t = 3.25，P = 0.002）。因此，在已确诊的中度高血压患者中，运动时的SBP对LVMI的预测性并不比静息时的SBP更好。
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