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Cyclosporin A, but not everolimus, inhibits DNA repair in human fibroblasts and lymphoblasts.

作者信息

Kuschal C, Thoms K-M, Mori T, Kobayashi N, Boeckmann L, Laspe P, Emmert S

机构信息

Department of Dermatology and Venerology, Georg-August-University, Gottingen, Germany.

出版信息

Int J Clin Pharmacol Ther. 2009 Jan;47(1):38-40. doi: 10.5414/cpp47038.

DOI:10.5414/cpp47038
PMID:19203533
Abstract
摘要

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Deregulation of XPC and CypA by cyclosporin A: an immunosuppression-independent mechanism of skin carcinogenesis.
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A modified fluorimetric host cell reactivation assay to determine the repair capacity of primary keratinocytes, melanocytes and fibroblasts.一种改良的荧光主体细胞再激活检测法,用于测定原代角质细胞、黑素细胞和成纤维细胞的修复能力。
BMC Biotechnol. 2010 Jun 22;10:46. doi: 10.1186/1472-6750-10-46.