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流感病毒之谜。

The influenza virus enigma.

作者信息

Salomon Rachelle, Webster Robert G

机构信息

Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN 38105-2678, USA.

出版信息

Cell. 2009 Feb 6;136(3):402-10. doi: 10.1016/j.cell.2009.01.029.

Abstract

Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues to kill both people and poultry in Eurasia. Here, we discuss the pathogenesis and transmissibility of influenza viruses and we emphasize the need to find better predictors of both seasonal and potentially pandemic influenza.

摘要

季节性流感和大流行性流感仍然对科学家和临床医生构成挑战。耐药性H1N1流感病毒在2009年流感季节占据主导地位,而H5N1禽流感病毒仍在欧亚大陆导致人和家禽死亡。在此,我们讨论流感病毒的发病机制和传播性,并强调需要找到更好的季节性流感和潜在大流行性流感的预测指标。

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