怀孕恒河猴器械操作的麻醉管理

Anesthetic management for instrumentation of the pregnant rhesus monkey.

作者信息

Sanders E A, Gleed R D, Nathanielsz P W

机构信息

Department of Physiology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.

出版信息

J Med Primatol. 1991 Jul;20(5):223-8.

PMID:1920377

Abstract

The anesthetic procedures used and the responses observed during maternal instrumentation on 38 pregnant rhesus monkeys (Macaca mulatta) during the second half of gestation are reported. A laparotomy with maternal instrumentation was performed in all animals. Anesthesia was induced with ketamine and maintained with halothane. Two animals delivered within five days of anesthesia and surgery and were unable to undergo experimentation. The remaining 36 animals underwent successful experimentation. Dysrhythmias, hypotension, and hypothermia were identified as complications of anesthesia.

摘要

报告了在38只妊娠后半期的恒河猴（猕猴）进行母体器械操作时所采用的麻醉程序以及观察到的反应。对所有动物均进行了伴有母体器械操作的剖腹术。麻醉诱导采用氯胺酮，维持采用氟烷。两只动物在麻醉和手术后五天内分娩，无法进行实验。其余36只动物实验成功。心律失常、低血压和体温过低被确定为麻醉并发症。