Ofluoglu Onder
Department of Orthopaedics, Lütfi Kirdar Research Hospital, Istanbul, Turkey.
Acta Orthop Belg. 2008 Dec;74(6):831-6.
The results of aggressive management of giant cell tumour including high speed burr, argon plasma cauterisation and phenolisation were reviewed. Twenty four patients with primary or recurrent tumours were treated with a standardised protocol. There were 14 women (56%) and 10 men (44%) with a mean age of 34 years (14 to 62). The defects created after curettage and local adjuvants were reconstructed with PMMA. Additionally, internal fixation was used in weight-bearing bones. Local recurrence occurred in only one patient. Two patients (8%) developed pulmonary metastases. Reconstruction failed only in one patient. These findings support that the combined use of local adjuvants in the treatment of giant cell tumour is a safe and effective way to reduce the rate of local recurrence.
回顾了包括高速磨钻、氩等离子体烧灼和酚化在内的巨细胞瘤积极治疗的结果。24例原发性或复发性肿瘤患者接受了标准化方案治疗。其中有14名女性（56%）和10名男性（44%），平均年龄34岁（14至62岁）。刮除术和局部辅助治疗后形成的缺损用聚甲基丙烯酸甲酯（PMMA）重建。此外，负重骨采用了内固定。仅1例患者出现局部复发。2例患者（8%）发生肺转移。仅1例患者重建失败。这些结果支持在巨细胞瘤治疗中联合使用局部辅助治疗是降低局部复发率的一种安全有效的方法。
