Lannsjö Marianne, af Geijerstam Jean-Luc, Johansson Ulla, Bring Johan, Borg Jörgen
Department of Neuroscience, Rehabilitation Medicine, Uppsala University, Sweden.
Brain Inj. 2009 Mar;23(3):213-9. doi: 10.1080/02699050902748356.
To describe symptom prevalence and structure after mild traumatic brain injury (MTBI) in a population-based cohort.
Symptoms data were collected at 3 months post-MTBI by use of the Rivermead Post-concussion Symptoms Questionnaire (RPQ) at follow-up of 2602 patients attending 39 Swedish hospitals. Spearmans rank correlation analysis was used to explore correlations between symptoms and structural equation modelling (SEM) was performed by use of several fit indices to explore if data were compatible with one or more factors.
Questionnaires were received from 2523 (97%) patients with a mean age of 31 years (median 22, range 6-96). A majority of the respondents (56%) reported no remaining injury related symptoms, 24% reported three or more symptoms and 10% reported seven or more symptoms. All symptoms exhibited strong positive inter-relations and SEM provided strong support for a single or two factor solution. Fit indices were only slightly weaker for three and four factor solutions.
A significant minority of patients reported multiple symptoms to persist at 3 months after MTBI. The observed structure of symptoms according to RPQ demonstrates a common factor for all symptoms, but also sub-groups of symptoms as previously suggested.
描述基于人群队列中轻度创伤性脑损伤（MTBI）后的症状患病率及症状结构。
在瑞典39家医院的2602例患者随访时，于MTBI后3个月使用Rivermead脑震荡后症状问卷（RPQ）收集症状数据。采用斯皮尔曼等级相关分析来探索症状之间的相关性，并通过使用多个拟合指数进行结构方程建模（SEM），以探究数据是否与一个或多个因素相符。
共收到2523例（97%）患者的问卷，患者平均年龄31岁（中位数22岁，范围6 - 96岁）。大多数受访者（56%）报告无残留的损伤相关症状，24%报告有三种或更多症状，10%报告有七种或更多症状。所有症状均表现出强烈的正相关关系，SEM为单因素或双因素解决方案提供了有力支持。对于三因素和四因素解决方案，拟合指数仅略弱。
少数患者报告在MTBI后3个月仍存在多种症状。根据RPQ观察到的症状结构表明，所有症状存在一个共同因素，但也如先前所示存在症状亚组。
