Waye John S, Walker Lynda, Nakamura Lisa M, Eng Barry, McFarlane Andrew
Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, ON, Canada.
Hemoglobin. 2009;33(1):51-3. doi: 10.1080/03630260802625659.
Routine hemoglobin (Hb) analysis identified a new beta chain Hb variant in an Iranian woman, who otherwise had normal hematological indices. Sequence analysis demonstrated that the Hb variant was due to a missense mutation at amino acid codon 117 (CAC>GAC, His-->Asp) of the beta-globin gene.
常规血红蛋白（Hb）分析在一名伊朗女性中发现了一种新的β链Hb变异体，该女性的其他血液学指标均正常。序列分析表明，这种Hb变异体是由β-珠蛋白基因第117位氨基酸密码子（CAC>GAC，组氨酸→天冬氨酸）的错义突变引起的。
