冰岛羔羊的实验性维斯纳病
Experimental Visna in Icelandic lambs.
作者信息
Pálsson P A, Georgsson G, Pétursson G, Nathanson N
出版信息
Acta Vet Scand. 1977;18(1):122-8. doi: 10.1186/BF03548472.
Icelandic lambs were inoculated intracerebrally with visna virus at 10 days of age and sacrificed 22–25 days after infection. Virus was isolated from all 5 inoculated animals, and pronounced periventricular lesions, typical of early visna, were seen in the 3 lambs with the most widespread infection. The response to the infection was very similar to that seen previously in adult Icelandic sheep. In addition, 2 uninoculated lambs housed with the injected animals and sacrificed at the same time also became infected.
冰岛羔羊在10日龄时脑内接种维斯纳病毒，并在感染后22 - 25天处死。从所有5只接种动物中都分离出了病毒，在3只感染最广泛的羔羊中可见明显的脑室周围病变，这是早期维斯纳病的典型症状。对感染的反应与之前在成年冰岛绵羊中观察到的非常相似。此外，与接种动物饲养在一起并同时处死的2只未接种羔羊也被感染。
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