Mamou Jonathan, Ramachandran Sarayu, Feleppa Ernest J
Frederic L Lizzi Center for Biomedical Engineering, Riverside Research Institute, New York, NY 10038, USA.
J Acoust Soc Am. 2008 Dec;124(6):EL347-52. doi: 10.1121/1.2993743.
Brachytherapy to treat prostate cancer uses transrectal ultrasound to guide implantation of titanium-shelled radioactive seeds. Transperitoneal implantation allows errors in placement that cause suboptimal dosimetry. Conventional ultrasound cannot reliably image implanted seeds; therefore, seed misplacements cannot be corrected in the operating room. Previously, an algorithm based on singular spectrum analysis was shown to image palladium seeds better than B-mode ultrasound could. The algorithm is now applied to imaging an iodine seed in gel and in beef tissue as a function of seed angle relative to the incident ultrasound. Results indicate that both seed types are imaged reliably by the algorithm.
近距离放射疗法治疗前列腺癌采用经直肠超声引导钛壳放射性粒子植入。经腹植入会导致粒子放置错误，从而造成剂量测定不理想。传统超声无法可靠地成像已植入的粒子；因此，粒子放置错误在手术室无法得到纠正。此前，一种基于奇异谱分析的算法在成像钯粒子方面比B型超声表现更好。现在该算法被应用于成像凝胶和牛肉组织中的碘粒子，作为粒子相对于入射超声角度的函数。结果表明，该算法能够可靠地成像这两种类型的粒子。
