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松质骨模拟体模中相速度和频散对体积分数的依赖性。

The dependencies of phase velocity and dispersion on volume fraction in cancellous-bone-mimicking phantoms.

作者信息

Wear Keith A

机构信息

US Food and Drug Administration, Center for Devices and Radiological Health, HFZ-142, Rockville, Maryland 20852, USA.

出版信息

J Acoust Soc Am. 2009 Feb;125(2):1197-201. doi: 10.1121/1.3050310.

DOI:10.1121/1.3050310
PMID:19206892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9125424/
Abstract

Frequency-dependent phase velocity was measured in eight cancellous-bone-mimicking phantoms consisting of suspensions of randomly oriented nylon filaments (simulating trabeculae) in a soft-tissue-mimicking medium (simulating marrow). Trabecular thicknesses ranged from 152 to 356 mum. Volume fractions of nylon filament material ranged from 0% to 10%. Phase velocity varied approximately linearly with frequency over the range from 300 to 700 kHz. The increase in phase velocity (compared with phase velocity in a phantom containing no filaments) at 500 kHz was approximately proportional to volume fraction occupied by nylon filaments. The derivative of phase velocity with respect to frequency was negative and exhibited nonlinear, monotonically decreasing dependence on volume fraction. The dependencies of phase velocity and its derivative on volume fraction in these phantoms were similar to those reported in previous studies on (1) human cancellous bone and (2) phantoms consisting of parallel nylon wires immersed in water.

摘要

在八个松质骨模拟体模中测量了频率依赖相速度,这些体模由随机取向的尼龙细丝(模拟小梁)悬浮于软组织模拟介质(模拟骨髓)中组成。小梁厚度范围为152至356微米。尼龙细丝材料的体积分数范围为0%至10%。在300至700千赫兹范围内,相速度随频率近似呈线性变化。在500千赫兹时,相速度的增加(与不含细丝的体模中的相速度相比)近似与尼龙细丝所占体积分数成正比。相速度相对于频率的导数为负,且对体积分数呈现出非线性、单调递减的依赖性。这些体模中相速度及其导数对体积分数的依赖性与先前关于(1)人松质骨和(2)由浸入水中的平行尼龙丝组成的体模的研究报告中的依赖性相似。

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本文引用的文献

1
Interference between wave modes may contribute to the apparent negative dispersion observed in cancellous bone.波模之间的干涉可能导致在松质骨中观察到的明显负色散。
J Acoust Soc Am. 2008 Sep;124(3):1781-9. doi: 10.1121/1.2953309.
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Instrumentation for in vivo ultrasonic characterization of bone strength.用于体内骨强度超声表征的仪器。
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Velocity dispersion of acoustic waves in cancellous bone.松质骨中声波的速度色散
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The effects of frequency-dependent attenuation and dispersion on sound speed measurements: applications in human trabecular bone.频率依赖性衰减和频散对声速测量的影响:在人松质骨中的应用
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Group velocity, phase velocity, and dispersion in human calcaneus in vivo.人体跟骨在体时的群速度、相速度和色散
J Acoust Soc Am. 2007 Apr;121(4):2431-7. doi: 10.1121/1.2697436.
7
Bayesian estimation of the underlying bone properties from mixed fast and slow mode ultrasonic signals.基于混合快、慢模式超声信号的潜在骨特性的贝叶斯估计。
J Acoust Soc Am. 2007 Jan;121(1):EL8-15. doi: 10.1121/1.2401198.
8
Variation of ultrasonic parameters with microstructure and material properties of trabecular bone: a 3D model simulation.超声参数随松质骨微观结构和材料特性的变化:三维模型模拟
J Bone Miner Res. 2007 May;22(5):665-74. doi: 10.1359/jbmr.070209.
9
Anomalous negative dispersion in bone can result from the interference of fast and slow waves.骨骼中异常的负色散可能由快波和慢波的干涉引起。
J Acoust Soc Am. 2006 Nov;120(5 Pt 1):EL55-61. doi: 10.1121/1.2357187.
10
Prediction of hip fracture risk by quantitative ultrasound in more than 7000 Swiss women > or =70 years of age: comparison of three technologically different bone ultrasound devices in the SEMOF study.7000多名70岁及以上瑞士女性中通过定量超声预测髋部骨折风险:SEMOF研究中三种技术不同的骨超声设备的比较
J Bone Miner Res. 2006 Sep;21(9):1457-63. doi: 10.1359/jbmr.060615.