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一种聚合物、开孔硬质泡沫的特性,模拟松质骨的超声特性。

Characterization of a polymer, open-cell rigid foam that simulates the ultrasonic properties of cancellous bone.

机构信息

Department of Physics, Rhodes College, Memphis, Tennessee 38112, USA.

College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

出版信息

J Acoust Soc Am. 2018 Feb;143(2):911. doi: 10.1121/1.5023219.

Abstract

Materials that simulate the ultrasonic properties of tissues are used widely for clinical and research purposes. However, relatively few materials are known to simulate the ultrasonic properties of cancellous bone. The goal of the present study was to investigate the suitability of using a polymer, open-cell rigid foam (OCRF) produced by Sawbones. Measurements were performed on OCRF specimens with four different densities. Ultrasonic speed of sound and normalized broadband ultrasonic attenuation were measured with a 0.5 MHz transducer. Three backscatter parameters were measured with a 5 MHz transducer: apparent integrated backscatter, frequency slope of apparent backscatter, and normalized mean of the backscatter difference. X-ray micro-computed tomography was used to measure the microstructural characteristics of the OCRF specimens. The trabecular thickness and relative bone volume of the OCRF specimens were similar to those of human cancellous bone, but the trabecular separation was greater. In most cases, the ultrasonic properties of the OCRF specimens were similar to values reported in the literature for cancellous bone, including dependence on density. In addition, the OCRF specimens exhibited an ultrasonic anisotropy similar to that reported for cancellous bone.

摘要

用于临床和研究目的的模拟组织超声特性的材料被广泛使用。然而,已知的能够模拟松质骨超声特性的材料相对较少。本研究的目的是研究使用聚合物、由 Sawbones 生产的开孔硬质泡沫(OCRF)的适用性。对具有四种不同密度的 OCRF 标本进行了测量。使用 0.5 MHz 换能器测量声速和归一化宽带超声衰减。使用 5 MHz 换能器测量了三个反向散射参数:表观积分反向散射、表观反向散射的频率斜率和反向散射差的归一化均值。X 射线微计算机断层扫描用于测量 OCRF 标本的微观结构特征。OCRF 标本的小梁厚度和相对骨体积与人类松质骨相似,但小梁分离更大。在大多数情况下,OCRF 标本的超声特性与文献中报道的松质骨值相似,包括对密度的依赖性。此外,OCRF 标本表现出与文献报道的松质骨相似的超声各向异性。

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Ultrasonic backscatter from cancellous bone: the apparent backscatter transfer function.松质骨的超声背向散射:表观背向散射传递函数
IEEE Trans Ultrason Ferroelectr Freq Control. 2015 Dec;62(12):2115-25. doi: 10.1109/TUFFC.2015.007299.
10
Signal of Interest Selection Standard for Ultrasonic Backscatter in Cancellous Bone Evaluation.松质骨评估中超声背散射感兴趣信号选择标准
Ultrasound Med Biol. 2015 Oct;41(10):2714-21. doi: 10.1016/j.ultrasmedbio.2015.06.005. Epub 2015 Jul 23.

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