Ord R, Coletti D
Department of Oral and Maxillofacial Surgery, University of Maryland Medical Center, Baltimore, MD 21201, USA.
Oral Dis. 2009 Mar;15(2):133-41. doi: 10.1111/j.1601-0825.2008.01496.x.
Necrotizing fasciitis of the cervical facial region is a rare entity that has seen an increasing prevalence in the last 20 years. It is most common in patients with an underlying systemic disease leading to immunosuppression, but can be seen in healthy adults and children. It is characterized by soft tissue destruction which is disproportionate to its clinical symptoms and signs, with rapid progression and fatal outcome, if not treated rapidly and radically. We present a review of the etio-pathogenesis and management of this challenging disease.
颈面部坏死性筋膜炎是一种罕见疾病,在过去20年中其发病率呈上升趋势。它在患有导致免疫抑制的潜在全身性疾病的患者中最为常见,但在健康的成人和儿童中也可见到。其特征是软组织破坏与其临床症状和体征不相称,如果不迅速、彻底地治疗,病情会迅速进展并导致致命后果。我们对这种具有挑战性的疾病的病因发病机制及治疗进行综述。