Sato E, Takeuchi K, Fujimori M, Tanaka S, Tanaka Y, Nishi S, Terai T, Ogata A
Department of Anesthesiology, Osaka Municipal Kita Citizens Hospital.
Masui. 1991 Jul;40(7):1102-6.
In a retrospective study of 222 patients who underwent transurethral resection of the prostate under spinal anesthesia, plasma sodium levels during the operation were examined. The weight of prostate resected, the volume of irrigating fluid used and the duration of the operative procedure influenced the changes in plasma sodium levels. But, these changes were not statistically significant. The rise in central venous pressure values was associated with the absorption of irrigating fluid as evidenced by a drop in plasma sodium. The central venous pressure was monitored in 77 patients. There was a statistically significant correlation between the degree of hyponatremia and the rise in central venous pressure (P less than 0.001). The rise in central venous pressure reflected a change in the patient's cardiovascular status and it was, therefore, possible to treat the hyponatremia quickly and effectively. Central venous pressure monitoring is helpful in determining hyponatremia before it becomes clinically manifest.
在一项对222例接受脊髓麻醉下经尿道前列腺切除术患者的回顾性研究中，检测了手术期间的血浆钠水平。切除的前列腺重量、所用冲洗液的体积和手术时间影响血浆钠水平的变化。但是，这些变化无统计学意义。血浆钠下降证明中心静脉压值升高与冲洗液的吸收有关。对77例患者进行了中心静脉压监测。低钠血症程度与中心静脉压升高之间存在统计学显著相关性（P<0.001）。中心静脉压升高反映了患者心血管状态的变化，因此，有可能快速有效地治疗低钠血症。中心静脉压监测有助于在低钠血症临床表现出来之前进行判定。
