Kikuchi N, Kawashima T, Yamagishi F, Suzuki K, Yasuda J, Niijima Y, Mizutani F, Tabeta H
Department of Internal Medicine, Chiba Kaihin Municipal Hospital.
Jpn J Antibiot. 1991 Aug;44(8):839-45.
The clinical efficacy of ciprofloxacin (CPFX) was investigated in pulmonary infections in patients with chronic respiratory diseases. Out of 58 cases collected, 54 were evaluable for utility of CPFX including 20 with pneumonia, 34 with chronic bronchial infection. CPFX was given orally at 200 mg 3 times per day. In 20 cases of pneumonia, the mean age was 62.0 years underlying diseases were chronic bronchitis 9, bronchiectasis 6, inactive pulmonary tuberculosis 4, and diffuse panbronchiolitis 1. The efficacy rate of CPFX in this group was 90.0%. In 34 cases of chronic bronchial infection, the mean age was 59.8 years, underlying diseases included bronchiectasis 10, chronic bronchitis 8, inactive pulmonary tuberculosis 7, diffuse panbronchiolitis 5, and pulmonary emphysema 4. The efficacy rate of CPFX in this group was 70.6%. The overall efficacy rate in the entire cases was 77.8%, and we consider CPFX to be effective in the treatment of patients with chronic respiratory diseases.
对环丙沙星（CPFX）治疗慢性呼吸道疾病患者肺部感染的临床疗效进行了研究。在所收集的58例病例中，54例可评估CPFX的效用，其中20例为肺炎，34例为慢性支气管感染。CPFX口服给药，剂量为每日3次，每次200mg。在20例肺炎患者中，平均年龄为62.0岁，基础疾病包括慢性支气管炎9例、支气管扩张6例、非活动性肺结核4例、弥漫性泛细支气管炎1例。该组CPFX的有效率为90.0%。在34例慢性支气管感染患者中，平均年龄为59.8岁，基础疾病包括支气管扩张10例、慢性支气管炎8例、非活动性肺结核7例、弥漫性泛细支气管炎5例、肺气肿4例。该组CPFX的有效率为70.6%。全部病例的总有效率为77.8%，我们认为CPFX对治疗慢性呼吸道疾病患者有效。
