Campana-Salort Emmanuelle
Centre de référence des maladies neuromusculaires et de la SLA, hôpital La Timone, 13385 Marseille Cedex 5, France.
Rev Prat. 2008 Dec 31;58(20):2245-52.
Despite major development of complementary investigations, diagnosis of muscular disorders is mainly clinical. Myopathies can present with unusual or atypical clinical features: myotonia, periodic paralysis, respiratory failure, swallowing difficulties, ptosis, ophtalmoplegia, camptocormia, distal or asymmetrical limb muscle weakness. It can be cause of inaccurate diagnosis. The clinical variability of muscular disorders must be recognized by physicians to drive diagnosis process and to offer an opportunity for early interventional management strategies. This paper reviews the main atypical clinical features of myopathies and their causes.
尽管补充检查有了重大进展，但肌肉疾病的诊断主要还是依靠临床症状。肌病可能表现出不寻常或非典型的临床特征：肌强直、周期性瘫痪、呼吸衰竭、吞咽困难、上睑下垂、眼肌麻痹、脊柱前凸、远端或不对称性肢体肌肉无力。这可能导致诊断不准确。医生必须认识到肌肉疾病的临床变异性，以便推动诊断过程，并为早期干预管理策略提供机会。本文综述了肌病的主要非典型临床特征及其病因。
