Alba Ana C, Delgado Diego H
Division of Cardiology and Transplantation, Toronto General Hospital, 585 University Avenue, 11c-1201, Toronto, ON, M5G 2N2, Canada.
Expert Rev Cardiovasc Ther. 2009 Feb;7(2):147-57. doi: 10.1586/14779072.7.2.147.
Coronary heart disease is the most common cause of heart failure. Its prevalence has increased mainly owing to the improved survival of patients after acute myocardial infarction. In patients with heart failure, the presence of coronary heart disease has been shown to be independently associated with worsened long-term outcomes, including hospitalizations and poor mortality. Coronary heart disease frequently coexists with several major risk factors for the onset and progression of heart failure, such as hypertension, diabetes, obesity and metabolic syndrome, among others. Medical efforts to reduce the incidence of heart failure burden in patients with coronary heart disease and other types of cardiomyopathies must be directed at the prevention of heart failure and coronary risk factors themselves, and not just at the improvement of the management of established disease. This article will address the impact of known risk factors in the development of coronary heart disease and heart failure.
冠心病是心力衰竭最常见的病因。其患病率上升主要归因于急性心肌梗死后患者生存率的提高。在心力衰竭患者中，冠心病的存在已被证明与长期预后恶化独立相关，包括住院和不良死亡率。冠心病常与心力衰竭发生和进展的几个主要危险因素并存，如高血压、糖尿病、肥胖和代谢综合征等。降低冠心病和其他类型心肌病患者心力衰竭负担发生率的医学努力必须针对心力衰竭和冠状动脉危险因素本身的预防，而不仅仅是改善已确诊疾病的管理。本文将探讨已知危险因素在冠心病和心力衰竭发生中的影响。
