Bulman-Fleming Julie C, Gibson Tom W, Kruth Stephen A
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.
J Am Vet Med Assoc. 2009 Feb 1;234(3):381-4. doi: 10.2460/javma.234.3.381.
A 9-year-old 6.9-kg (15.18-lb) castrated male Siamese cat was evaluated because of a 3-year history of repeated hemorrhage from the right metacarpal pad.
Physical examination findings were unremarkable except for a 2-mm-diameter erosion of the right metacarpal pad. A CBC revealed marked thrombocytopenia. Serum biochemical analyses, retroviral screening, thoracic radiography, and abdominal ultrasonography revealed no abnormalities. Via ultrasonographic examination, the vasculature in the right metacarpal pad appeared increased, compared with that of the left pad; an aberrant arterial plexus that was confined to the metacarpal pad was identified via arterial angiography.
Surgical resection of the metacarpal pad (without digital pad transposition) with primary closure was performed. Histologic evaluation of the pad tissue revealed invasive cutaneous angiomatosis. The incision healed without complications, and limb function was considered normal. Administration of prednisone (2 mg/kg [0.91 mg/lb], PO, q 24 h) was initiated 4 weeks prior to surgery to treat suspected immune-mediated thrombocytopenia and continued afterwards with a tapering dosage. Platelet count was within reference limits 4 months after surgery; at 12 months, there was no evidence of recurrence of abnormal vasculature in the right metacarpal pad region.
Complete resection of the metacarpal pad (without pad transposition) resulted in successful and well-tolerated treatment of cutaneous angiomatosis of the metacarpal pad of a cat. Recurrence of abnormal vasculature was not evident at a 12-month follow-up examination. Thrombocytopenia is commonly associated with vascular anomalies in humans and may have been a contributing factor in this cat.
一只9岁、体重6.9千克（15.18磅）的去势雄性暹罗猫因右掌垫反复出血3年而接受评估。
体格检查结果无异常，仅右掌垫有一个直径2毫米的糜烂面。血常规显示明显的血小板减少。血清生化分析、逆转录病毒筛查、胸部X光检查和腹部超声检查均未发现异常。通过超声检查，与左掌垫相比，右掌垫的血管系统似乎增多；通过动脉血管造影发现了一个局限于掌垫的异常动脉丛。
进行了掌垫的手术切除（未进行趾垫移位）并一期缝合。对掌垫组织进行组织学评估显示为侵袭性皮肤血管瘤病。切口愈合无并发症，肢体功能被认为正常。在手术前4周开始给予泼尼松（2毫克/千克[0.91毫克/磅]，口服，每24小时一次）以治疗疑似免疫介导的血小板减少症，术后继续给予逐渐减量的药物。术后4个月血小板计数在参考范围内；在12个月时，右掌垫区域没有异常血管复发的迹象。
掌垫的完全切除（未进行趾垫移位）成功且耐受性良好地治疗了猫掌垫的皮肤血管瘤病。在12个月的随访检查中未发现异常血管复发。血小板减少症在人类中通常与血管异常有关，可能是这只猫发病的一个因素。
