Smith Matthew P Welberry, Spark James Ian, Patel Jai V, Border David J, Oswal Dilip, Lewington Andrew J P
Department of Renal Medicine, The Leeds Teaching Hoispitals NHS Trust, UK.
Hemodial Int. 2009 Jan;13(1):3-5. doi: 10.1111/j.1542-4758.2009.00349.x.
Use of depopulated bovine ureteric xenografts for hemodialysis vascular access has recently been described. Cellular components have been removed, giving a connective tissue matrix which can be neocellularized, retaining native biomechanics. A 24-year-old male with end-stage renal disease from focal segmental glomerulosclerosis presented with particularly difficult vascular access. A depopulated bovine ureteric xenograft was implanted from the left subclavian artery to innominate vein. It became massively aneurysmal, requiring emergency embolization. Biopsy of the graft stained positive for alpha-gal. We believe this is the first reported case of massive aneurysmal dilatation of a depopulated bovine ureteric xenograft.
最近有关于使用去细胞牛输尿管异种移植物建立血液透析血管通路的报道。细胞成分已被去除，形成了一种可重新细胞化的结缔组织基质，并保留了天然生物力学特性。一名24岁患有局灶节段性肾小球硬化症所致终末期肾病的男性，其血管通路建立特别困难。将一个去细胞牛输尿管异种移植物从左锁骨下动脉植入无名静脉。它出现了巨大动脉瘤样扩张，需要紧急栓塞治疗。移植物活检α-半乳糖染色呈阳性。我们认为这是首例关于去细胞牛输尿管异种移植物发生巨大动脉瘤样扩张的报道病例。
