Section of Biosciences, Department of Cell Biology and Regulation, Karl Marx University, 7010 Leipzig, GDR.
J Neuroendocrinol. 1989 Aug 1;1(4):305-8. doi: 10.1111/j.1365-2826.1989.tb00120.x.
Abstract The central release of both oxytocin and vasopressin within the septum and dorsal hippocampus in response to suckling was studied in conscious, freely-behaving lactating rats. Three consecutive 30-min push-pull perfusions were carried out before, during and after suckling (suckled group) or without suckling (control group). As compared to control levels, suckling resulted in a significantly increased oxytocin release within both limbic brain areas (septum: to 140%, dorsal hippocampus: to 1,600%). After removal of the suckling pups, the oxytocin concentration in the final perfusates remained at the stimulation level (septum) or tended to return to control values (dorsal hippocampus). In contrast to oxytocin, the vasopressin perfusate levels did not differ significantly between unsuckled and suckled rats.
摘要 在清醒、自由活动的哺乳期大鼠中研究了吸吮刺激引起的隔核和背海马中海马催产素和加压素的中枢释放。在吸吮（吸吮组）或不吸吮（对照组）之前、期间和之后连续进行了 3 次连续 30 分钟的推挽灌流。与对照组水平相比，吸吮导致两个边缘脑区的催产素释放明显增加（隔核：增加 140%，背海马：增加 1600%）。在移除哺乳幼仔后，最后一次灌流中的催产素浓度仍保持在刺激水平（隔核）或趋于恢复到对照值（背海马）。与催产素相反，未吸吮和吸吮大鼠之间的加压素灌流水平没有显著差异。
