Laboratory of Cell Biology, Building 36, Room 2D10, Bethesda, Maryland 20892, USA.
J Neuroendocrinol. 1989 Apr 1;1(2):79-82. doi: 10.1111/j.1365-2826.1989.tb00083.x.
The distribution of mRNA transcripts for the six known protein kinase C (PKC) genes has been investigated by quantitative in situ hybridization histochemistry. PKC-delta transcripts were detected only in the thalamus and PKC-zeta was found in several areas including the supraoptic (SON) and paraventricular (PVN) nuclei. Activation of magnocellular cells in the SON and PVN following 7 days of saline-loading resulted in increased levels of PKC-zeta transcripts in both of these nuclei.
通过定量原位杂交组织化学研究了六种已知蛋白激酶 C（PKC）基因的 mRNA 转录本的分布。仅在丘脑检测到 PKC-δ 转录本，而 PKC-ζ 则存在于包括视上核（SON）和室旁核（PVN）在内的多个区域。盐水负荷 7 天后，SON 和 PVN 中的大细胞激活导致这两个核中 PKC-ζ 转录本水平升高。
