Hyman E S
Touro Research Institute, New Orleans, Louisiana, USA.
Biophys J. 1966 Jul;6(4):405-10. doi: 10.1016/S0006-3495(66)86666-3. Epub 2008 Dec 31.
It is likely that sodium and potassium must traverse a lipid membrane surrounding cells and that this membrane has to do with intracellular cation selection. Electrolyte theory is inadequate to predict the partition of salts of these cations between water and a lipid phase. The data obtained here demonstrate the partition and the cation selection to be a function of the anion species (or ionized lipid), the solvent and the presence of the unionized form of the lipid. Specificity in lipid partition is not synonymous with the cation specificity in precipitation of ionic crystals.
钠和钾很可能必须穿过围绕细胞的脂质膜,并且这种膜与细胞内阳离子的选择有关。电解质理论不足以预测这些阳离子的盐在水相和脂质相之间的分配。此处获得的数据表明,分配和阳离子选择是阴离子种类(或离子化脂质)、溶剂以及脂质非离子化形式的存在的函数。脂质分配的特异性与离子晶体沉淀中的阳离子特异性并不同义。