Kunz A L, Coulter N A
Department of Physiology, The Ohio State University, Columbus, Ohio, USA.
Biophys J. 1967 Jan;7(1):25-36. doi: 10.1016/S0006-3495(67)86573-1. Epub 2008 Dec 31.
Sinusoidal oscillatory flow of blood and of aqueous glycerol solutions was produced in rigid cylindrical tubes. For aqueous glycerol, the amplitude of the measured pressure gradient wave form conformed closely to that predicted by Womersley's theory of oscillatory flow, up to Reynolds numbers approaching 2000. Blood differed significantly from aqueous glycerol solutions of comparable viscosity, especially at low frequencies and high hematocrits. As frequency increased, the hydraulic impedance of blood decreased to a minimum at a frequency of about 1-2 CPS, increasing monotonically at higher frequencies. The dynamic apparent viscosity of blood, calculated from Womersley's theory, decreased with increasing flow amplitude. The reactive component of the hydraulic impedance increased with frequency as predicted by theory; the resistive component decreased with increasing frequency, differing from the resistance of a Newtonian fluid which increased with frequency.
在刚性圆柱管中产生了血液和甘油水溶液的正弦振荡流。对于甘油水溶液,在雷诺数接近2000之前,测量的压力梯度波形的幅度与沃默斯利振荡流理论预测的结果非常吻合。血液与具有可比粘度的甘油水溶液有显著差异,特别是在低频和高血细胞比容时。随着频率增加,血液的水力阻抗在约1 - 2赫兹的频率下降至最低,在更高频率下单调增加。根据沃默斯利理论计算的血液动态表观粘度随流量幅度增加而降低。水力阻抗的电抗分量如理论预测的那样随频率增加;电阻分量随频率增加而降低,这与牛顿流体的阻力随频率增加不同。