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公共蛋白质组学质谱库和流程的最新进展。

Recent developments in public proteomic MS repositories and pipelines.

作者信息

Mead Jennifer A, Bianco Luca, Bessant Conrad

机构信息

Cranfield Health, Cranfield University, Cranfield, UK.

出版信息

Proteomics. 2009 Feb;9(4):861-81. doi: 10.1002/pmic.200800553.

Abstract

This article provides an overview of publicly available proteomic data repositories in a single document with a particular focus on the latest developments, many of which are not announced through traditional publications. The review is intended to inform the proteomics practitioner of the options for storage and dissemination of their MS/MS data in the public domain, and to help those who want to mine proteomic data generated by others. The latter area has arguably seen the most development in recent times, as repositories have sprouted new tools for data analysis, visualisation and experimental design. We also highlight key biological datasets available at each repository, including standard datasets. Finally, we touch upon areas of significant challenge and future directions.

摘要

本文在一篇文档中概述了公开可用的蛋白质组学数据存储库,特别关注最新进展,其中许多进展并非通过传统出版物发布。本综述旨在告知蛋白质组学从业者在公共领域存储和传播其MS/MS数据的选项,并帮助那些想要挖掘他人生成的蛋白质组学数据的人。可以说,后一个领域是近年来发展最为迅速的领域,因为存储库涌现出了用于数据分析、可视化和实验设计的新工具。我们还重点介绍了每个存储库中可用的关键生物学数据集,包括标准数据集。最后,我们探讨了重大挑战领域和未来方向。

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