与系统性红斑狼疮相关的努南综合征。
Noonan syndrome associated with systemic lupus erythematosus.
作者信息
Lisbona M P, Moreno M, Orellana C, Gratacos J, Larrosa M
机构信息
Unitat de Reumatologia, Hospital de Sabadell, Institut Universitari Parc Taulí (UAB), Sabadell (Barcelona), Spain.
出版信息
Lupus. 2009 Mar;18(3):267-9. doi: 10.1177/0961203308094996.
Noonan syndrome (NS) is a developmental disorder characterised mainly by cardiac defects and craniofacial dysmorphia. An association between NS and some autoimmune diseases, such as thyroiditis and systemic lupus erythematosus (SLE), has been suggested. We report the case of a 28-year-old man with a diagnosis of NS and autoimmune hypothyroidism who developed symptoms and immunologic features of SLE.
努南综合征（NS）是一种发育障碍，主要特征为心脏缺陷和颅面部畸形。已有研究提示NS与某些自身免疫性疾病，如甲状腺炎和系统性红斑狼疮（SLE）之间存在关联。我们报告了一例28岁男性病例，该患者诊断为NS和自身免疫性甲状腺功能减退症，之后出现了SLE的症状和免疫学特征。
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