电刺激外侧杏仁核仅在戊巴比妥钠麻醉的雄性大鼠中引起六种垂体前叶激素中的生长激素分泌。
Electrical stimulation of the basolateral amygdala elicits only growth hormone secretion among six anterior pituitary hormones in the pentobarbital-anesthetized male rat.
机构信息
Department of Physiology, Institute of Endocrinology, Gunma University, Maebashi 371, Japan.
出版信息
J Neuroendocrinol. 1991 Dec 1;3(6):685-7. doi: 10.1111/j.1365-2826.1991.tb00334.x.
Abstract In order to investigate the role of the basolateral amygdala on secretion of the adenohypophyseal hormones, the basolateral amygdala was electrically stimulated for 10 min through a chronically implanted electrode in the pentobarbital-anesthetized adult male rat. Blood samples were withdrawn through a Silastic cannula implanted in the right atrium. Electrical stimulation of the basolateral amygdala increased plasma growth hormone, decreased plasma follicle-stimulating hormone and suppressed the increase in plasma adrenocorticotropin. Plasma prolactin, thyroid-stimulating hormone and luteinizing hormone were not significantly changed. These results indicate that electrical stimulation of the basolateral amygdala in the pentobarbital-anesthetized adult male rat causes a simultaneous change in secretion of several adenohypophyseal hormones.
摘要
为了研究基底外侧杏仁核在腺垂体激素分泌中的作用，通过在戊巴比妥钠麻醉的成年雄性大鼠中植入的慢性电极对基底外侧杏仁核进行了 10 分钟的电刺激。通过植入右心房的硅橡胶套管抽取血样。基底外侧杏仁核的电刺激增加了血浆生长激素，降低了血浆促卵泡激素，并抑制了血浆促肾上腺皮质激素的增加。血浆催乳素、促甲状腺激素和黄体生成素没有明显变化。这些结果表明，戊巴比妥钠麻醉的成年雄性大鼠基底外侧杏仁核的电刺激会导致几种腺垂体激素分泌的同时变化。
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