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泰国某三级医疗中心剖宫产子宫切除术的危险因素:一项病例对照研究。

Risk factors for cesarean hysterectomy in tertiary center in Thailand: a case-control study.

作者信息

Yamasmit Waralak, Chaithongwongwatthana Surasith

机构信息

Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration (BMA) Medical College, Bangkok, Thailand.

出版信息

J Obstet Gynaecol Res. 2009 Feb;35(1):60-5. doi: 10.1111/j.1447-0756.2008.00837.x.

DOI:10.1111/j.1447-0756.2008.00837.x
PMID:19215549
Abstract

AIM

To identify the risk factors for cesarean hysterectomy in a tertiary center in Bangkok, Thailand.

METHODS

A case-control study was conducted by reviewing the medical records of pregnant women delivered at BMA Medical College and Vajira Hospital between 1 January 2001 and 28 February 2007. The case refers to pregnant women who underwent hysterectomy immediately or within 24 h following cesarean delivery. Controls included pregnant women who received cesarean section during the same study period by a ratio of 1:5 (case : control).

RESULTS

During the study period, cesarean hysterectomy complicated 30 deliveries out of 31 106 deliveries (0.96:1000). Independent risk factors for cesarean hysterectomy from a multivariate logistic regression analysis were placental adherence (odds ratio [OR] = 440, 95% confidence interval [CI] 28-7000), placenta previa (OR = 57, 95% CI 6.0-540) and uterine atony (OR = 37, 95% CI 7.5-190). Sixty-three percent (5/8) of placental adherence were associated with placenta previa. Of these five patients, four had a uterine scar from a prior cesarean section. The following outcomes were significantly higher in the cesarean hysterectomy group as compared to the controls: operative time, blood loss, hypovolemia, coagulopathy, transfusions, febrile morbidity, secondary surgery, and duration of hospitalization.

CONCLUSION

Placental adherence, placenta previa and uterine atony were identified as significant risk factors for cesarean hysterectomy. Cesarean section due to placenta previa should be electively scheduled with well-prepared blood components. The obstetrician should provide counsel and obtain detailed informed consent with regard to the possibility of cesarean hysterectomy.

摘要

目的

确定泰国曼谷一家三级医疗中心剖宫产子宫切除术的危险因素。

方法

通过回顾2001年1月1日至2007年2月28日在BMA医学院和瓦吉拉医院分娩的孕妇的病历进行病例对照研究。病例组指剖宫产术后立即或24小时内接受子宫切除术的孕妇。对照组包括在同一研究期间接受剖宫产的孕妇,病例与对照的比例为1:5。

结果

在研究期间,31106例分娩中有30例发生剖宫产子宫切除术(0.96:1000)。多因素逻辑回归分析显示,剖宫产子宫切除术的独立危险因素为胎盘粘连(比值比[OR]=440,95%置信区间[CI]28 - 7000)、前置胎盘(OR = 57,95%CI 6.0 - 540)和子宫收缩乏力(OR = 37,95%CI 7.5 - 190)。63%(5/8)的胎盘粘连与前置胎盘有关。这5例患者中,4例有既往剖宫产子宫瘢痕。与对照组相比,剖宫产子宫切除组的以下结局显著更高:手术时间、失血量、低血容量、凝血功能障碍、输血次数、发热性疾病、二次手术和住院时间。

结论

胎盘粘连、前置胎盘和子宫收缩乏力被确定为剖宫产子宫切除术的重要危险因素。因前置胎盘行剖宫产应择期进行,并准备好充足的血液成分。产科医生应就剖宫产子宫切除术的可能性提供咨询并获得详细的知情同意。

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