Balster Robert L, Cruz Silvia L, Howard Matthew O, Dell Colleen A, Cottler Linda B
Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA 23298-0310, USA.
Addiction. 2009 Jun;104(6):878-82. doi: 10.1111/j.1360-0443.2008.02494.x. Epub 2009 Feb 10.
Many hundreds of household and industrial products can be volatilized readily and are subject to abuse. Inhalant abuse research has been hampered by a lack of consensus on whether or not there are subclassifications of abused inhalants based on chemical structure, form or intended use of the product or pharmacological properties. This paper discusses strengths and weaknesses of various approaches to classification of inhalants and suggests areas for future research in this area. It is concluded that classification of inhalants by form or product types is not useful for scientific purposes; rather, subclassification of inhalants should be based on a yet-to-be-determined combination of chemical and pharmacological similarity and shared patterns of abuse. One of the ways in which we can improve our understanding of inhalant abuse is to obtain more detailed information on individual products and chemicals, their patterns of use and the geographical distribution of their use.
数百种家用和工业产品很容易挥发，并且容易被滥用。吸入剂滥用研究受到阻碍，原因是对于基于化学结构、产品形式或预期用途或药理特性的滥用吸入剂是否存在亚分类缺乏共识。本文讨论了吸入剂分类的各种方法的优缺点，并提出了该领域未来研究的方向。得出的结论是，按形式或产品类型对吸入剂进行分类对科学目的没有用处；相反，吸入剂的亚分类应基于尚未确定的化学和药理学相似性以及共同滥用模式的组合。我们能够增进对吸入剂滥用理解的方法之一是获取有关单个产品和化学品、它们的使用模式以及使用的地理分布的更详细信息。
